It is against the trend. Yet remembering the history of the term "Disruptive Technology", it became widely popular around 2014, and was oftentimes referred to a literally "ground breaking technology" called "Continuous Disruption Ultra-high Pressure Shale Oil and Gas Mining Method", when a chemical solution (toxic) is pumped in the Earth's crust under immense pressures (~12,500 psi). Then it breaks the pockets with oil and gas for further delivery of those to us, our cars, power stations and finally burning all of this, eventually delivering tons of carbon dioxide in the air (sweet, isn't it?) including methane, which is 34 times worse as a greenhouse effect promoter than the CO2!. There many other negative effects of this technology on the environment, besides any escape of those gasses, which are not limited to the soil, rivers, underground water (you name it) pollutions...
Yay!!! Hail to a disruptive technology, my friends!!!
(The way I see it, tech people are willingly popularizing the term, invented (!) and widely used by the oil companies)
Disruptive innovation is a term in the field of business administration which refers to an innovation that creates a new market and value network and eventually disrupts an existing market and value network, displacing established market leading firms, products, and alliances.  The term was defined and first analyzed by the American scholar Clayton M. Christensen and his collaborators beginning in 1995, and has been called the most influential business idea of the early 21st century.
i think the terms "groundbreaking" and "disrupt the status quo" go back before 2014. So yes, its ethical to work on groundbreaking tech, but perhaps that particular tech is not ethical.
Disruptive is what breaks traditions and brings you new things. So the answer to the question is yes, because disruptive technologies make life easier for your consumers and businesses should always strive work towards it.